agnyaashaya

agnyaashaya
Illu pancrease hindi.JPG
Illu pancreas duodenum.jpg
1: agnyaashaya ka shir
2: agnyaashaya ki unsinet prakriya
3: agnyaashaya ka kanth
4: agnyaashaya ka dhad
5: agnyaashaya ki agragaami satah
6: agnyaashaya ki avar satah
7: agnyaashaya ka uchchatar kinaara
8: agnyaashaya ka agrim kinaara
9: agnyaashaya ka avar kinaara
10: omeinti gaaainth
11: agnyaashaya ki puchh
12: laghvaantraagr
gre ki sharee‍aariki subject #251 1199
dhamani avar agnyaashayalaghvaantraagri dhamani, agragaami agnyaashayalaghvaantraagri dhamani, plaihik dhamani
shira agnyaashayalaghvaantraagri shiraaeain, agnyaashayi shiraaeain
tantrika agnyaashayi tantujaal, audareeya gaingliya, vegas[1]
poorvagaami agnyaashayi kaliyaaain
emaiesaech agnyaashaya
dorlainds/elseeviyr agnyaashaya

agnyaashaya kasheruki jeevon ki paachan va ant:sraavi pranaali ka ek granthi ang hai. ye insulin, glukaagon, va somaatostaatin jaise kai zaroori haarmon banaane waali ant:sraavi granthi hai aur saath hi yeh agnyaashayi ras nikaalne waali ek bahi:sraavi granthi bhi hai, is ras mein paachak kinvak hote hain jo laghvaantr mein jaate hain. ye kinvak amlaann mein carbohydrate, proteen, va vasa ka aur bhanjan karte hain.

anukram

ootiki

sookshmadarshi ke neeche, agnyaashaya ke dage hue kaat mein do alag tarah ke mrudootak (paireinkaaima) ootak dikhte hain.[2] halke daag waali koshikaaon ke jhundon ko aailets of leingarhans kehte hain, ye vah haarmon banaate hai jo agnyaashaya ke ant:sraavi kriyaakalaapon ko karte hain. gaadhe daag waali koshikaaeain guchhik hoti hain jo bahi:sraavi nalikaaon se judti hain. guchhik koshikaaeain bahi:sraavi agnyaashaya ka hissa hain aur ve nalikaaon ki pranaali ke jariye aaaintadiyon mein paachak kinvak risaati hain.

banaavat shaklosoorat kaaryasamooh
aailets of leingarhans halke daag, bade, vrutteeya jhund haarmon utpaadan va risaav (ant:sraavi agnyaashaya)
agnayaashayi guchhik gaadhe daag, chhote, ber-jaise jhundh paachak kinvak utpaadan va risaav (bahi:sraavi agnyaashaya)

kaaryakalaap

agnyaashaya ek dvi-kaaryeeya granthi hai, ismein ant:sraavi granthi va bahi:sraavi granthiyon - donon ke kaarya hote hain.

ant:sraavi

ant:sraavi kriyaakalaapon wala agnyaashaya mein kuchh 10 lakh[3] koshika jhund hain jinhein aailets of leingarhaans kehte hain. aaileton mein chaar mukhya prakaar ki koshikaaeain hain. maanak daageekaran vidhiyon se inhein bhinnit karna thoda kathin hai, lekin inhein risaav ke aadhaar par vargeekrut kiya ja sakta hai: α - alfa koshikaaeain glookaagon, β beeta koshikaaeain insulin, δ delta koshikaaeain somaatostetin aur peepi koshikaaeain agnyaashayi pauleepeptaaid ka risaav karti hain.[4]

aailet ant:sraavi koshikaaon ka ek saghan samuchchaya hai jo ki jhundon aur doriyon mein aayojit hote hain aur inke aaspaas aadi tirchhi keshikaaon ka ek ghana jaal hota hai. aaileton ki keshikaaon mein ant:sraavi koshikaaon ki paraton ka astar hota hai jo vaahiniyon se seedhe sampark mein rahane ke liye saaitoplaasmi prakriyaaon ya seedhe ekaanvayan ka prayog karta hai. elan E. nors ki shareer naamak pustak ke anusaar,[5] ye aailet "athak roop se apne haarmon banaane mein lage rahate hai aur aamtaur par aaspaas ki agnyaashayi koshikaaon ko najrandaaj karte hain, maano ve shareer ke bilkul alag hi ang mein hon."

bahi:sraavi

ant:sraavi agnyaashaya rakt mein haarmonon ka risaav karta hai to bahi:sraavi agnyaashaya, laghvaantr ke haarmonon sikretin va kolisistokaainin ki pratikriyaasvaroop, paachak kinvak aur ek kshaareeya taral agnyaashayi ras utpann karta hai aur bahi:sraavi vaahiniyon ke jariye unka laghvaantr mein risaav kar deta hai. paachak kinvakon mein tripsin, kimotripsin, agnyaashayi laaipes va agnyaashayi emiles shaamil hain aur inka utpaadan aur risaav bahi:sraavi agnyaashaya ki guchhik koshikaaon dvaara hota hai. agnyaashayi vaahiniyon ke astar kuchh khaas koshikaaon ke bane hote hain, inhein seintroesinaar koshikaaeain kehte hain aur ye baaikaarbanet va lavan mein dhani ghol ka laghvaantr mein risaav karti hain. [6]

niyantran

agnyaashaya niyamit roop se rakt mein haarmonon ke jariye va svachaalit snaayutantr ke jariye niyamit roop se tantrika bharan praapt karta rahata hai. ye dono nivishtiyaaain agnyaashaya ki risaav gatividhiyon ko niyantrit karti hai.

sahaanubhootik (edrinrjik) asahaanubhootik (muskaarinik)
alfa 2: beeta koshikaaon se risaav kam karta hai, alfa koshikaaon se risaav badhaata hai M 3[7] alfa koshikaaon va beeta koshika se uttejana badhaata hai.

agnyaashaya ke rog

agnyaashaya bahut se paachak kinvakon ka bhandaar hai at: angnyaashaya mein kshati bahut haanikaarak ho sakti hai. agnyaashaya mein chhed hone par turant aupachaarik hastakshep ki zaroorat hoti hai.

agnyaashaya mein cheera lagaane ko painkriyetotomi kehte hain.

itihaas

agnyaashaya ki pehchaan sabse pehle heerofils (335-280 E.poo.), ne ki thi, jo ki ek yoonaani shareer rachana vigyaani shalyachikitsak the. kuchh sau saal baad ek aur yoonaani shareer rachana vigyaani rufos, ne is ang ko yoonaani naam painkriyaas diya yeh shabd yoonaani πaᾶaν pain arthaat "sab", "poorn", va κaaρaaέaaαaaς kreaas, arthaat "maaains" se bana hai[8]

bhroonavijnyaaaneeya vikaas

yojana vishay chitr, jo agnyaashaya ka prushtheeya va udareeya kali se vikaas darshaata hai. paripkvata ke samay udareeya kali pet ki naali (teer) ke doosari taraf palat jaati hai jahaaain vah aamtaur par prushtheeya paali se sammishrit ho jaati hai. ek atirikt udareeya lob, jo vikaas ke samay pratyaavartit hota hai, mit jaata hai.

agnyaashaya bhrooneeya agraantr se banta hai at: yeh antastatvak mool ka hai. agnyaashayi vikaas ki shuruaat se udareeya va prushtheeya moolaroop (ya kaliyon) ka nirmaan hota hai. har sanrachana angraantr se ek vaahini ke jariye sanchaar karti hai. udareeya agnayaashayi kali shir va ghumaavadaar prakriya banti hai aur yakruteeya chhidr se niklati hai.

udareeya va prushtheeya agnyaashayi kaliyon ka vibhedi ghoornan va sammashran hone se spasht roop se agnyaashaya ka nirmaan hota hai.[9] jaise jaise laghvaantraagr daain taraf ghoomta hai, vah apne saath prushtheeya agnyaashayi kali va aam pitt vaahini ko saath le jaata hai. apne antim gantavya tak pahuainchane ke baad udareeya agnyaashayi kali adhik badi prushtheeya agnyaashayi kali ke saath sammishrit ho jaati hai. sammishran ke samay udareeya va prushtheeya agnyaashaya ki mukhya vaahiniyaaain sammishrit ho jaati hain aur isse virsang ki vaahini banti hai jo ki mukhya agnyaashayi vaahini hai.

agnyaashaya ki koshikaaon ka bhinneekaran do alag pathon se hota hai, ye agnyaashaya ki dohare kaaryon - ant:sraavi va bahi:sraavi ke anuroop hai. bahi:sraavi agnyaashaya ki janak koshikaaon mein bhinneekaran karne vaale mahattvapoorn yogik hain folistenin, fibroblaast vikaas kaarak va nauch praapak pranaali.[9] bahi:sraavi guchhikaaon ka vikaas teen avasthaaon se gujrata hai. ye hain bhinneekaran-poorv, praarambhik bhinneekrut, va bhinneekrut avasthaaeain, jo ki kramash: anabhijnyaeya, kam va adhik paachan kinvak gatividhi darshaati hain.

ant:sraavi agnyaashaya ki janak koshikaaeain bahi:sraavi agnyaashaya ki praarambhik bhinneekrut avastha ki koshikaaeain hain.[9] nyoorojenin-3 va aaiesael-1 ke prabhaav mein par nauch praapak sanketan ki anupasthiti mein, ye koshikaaeain bhinnit ho ke samarpit ant:sraavi koshikaaon ke janakon ki do panktiyaaain banaati hain. pehli pankti, paiks-0 ke nirdesh mein alfa va gaama koshikaaeain banaati hain, jo kramash: glookaagon va agnyaashayi pauleepeptaaid naamak peptaaid banaati hain. doosari pankti paiks-6 se prabhaavit ho ke beeta va delta koshikaaeain banaati hain, jo kramash: insulin va somaatostetin banaati hain.

bhroon ke vikaas ke chauthe ya paaainchavein maas mein bhroon ke parisancharan mein insulin va glookaagon paaya ja sakta hai.[9]

atirikt chhaviyaaain

sandarbh

  1. emaseeji mein shareer rachana vigyaan 6/6ch2/s6ch2_30
  2. bi.you par ootak vigyaan 10404loa
  3. helamain bi, gilf E, grepengiyessar E, dainsk H, salehi A (2007). "[insulin ka dolana--laakshanik drushti se mahattvapoorn laya. madhumeh avarodhiyon ko insulin chhodne ke spandaneeya bhaag ko badhaana chaahiye]" (sveedish mein). lakaartningen 104 (32-33): 2236-9. PMID 17822201.
  4. beeaaraes shareer kriya vigyaan 4tha sanskaran, prushth 255-256, linda S konsteinjo, lipinkaut prakaashan
  5. shareer, lekhak elan E. nors, time-laaif vigyaan pustakaalaya shrunkhala (pru. 171) mein.
  6. metran, enthiya; jeen hopkins, Charles William mekalaaflin, soojn jaansan, maaryaana kvon vaarnar, David laahaart, jil di. right (1993). maanav jeev vigyaan va svaasthya. engalavud klifs, new jersey, sanyukt raajya amareeka: preintis haal. aai॰aऍsa॰abee॰aऍna॰ 0-13-981176-1. OCLC 32308337.
  7. verspohl ije, teke aar, mutshler E, leinbrekht ji (1990). "mooshak agnyaashayi aaileton mein muskaareeya praapak upaprakaar: bandhan va kaaryasanbandhi adhyayan". Euro. j. faarmaakol. 178 (3): 303-11. doi:10.1016/0014-2999(90)90109-J+. PMID 2187704.
  8. haarpar, dagalas. "painkriyaas". onlaain naamakaran shabdakosh. http://www.etymonline.com/index.php?term=pancreas. abhigman tithi: 2007-04-04.
  9. a aa i E kaarlsan, Bruce M. (2004). maanaveeya bhroom vigyaan va vikaaseeya jeev vigyaan. seint Louis: mosbi. pp. 372-4. aai॰aऍsa॰abee॰aऍna॰ 0-323-01487-9.

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